Run for office? No. I've slept with too many women, I've done too many drugs, and I've been to too many parties.

Whatever you do, don’t wake up at 65 years old and think about what you should have done with your life.

There are some scenes that you have to lose in order to win something at the end. A good director will keep pointing you that way, but it is also your job as an actor to understand that there are scenes that you do, particularly when you are the lead, where other people get to come in and steal and you have to let them. I understand that but a good director always reminds you where those moments are.

The owner of a local cannabis café told reporters George Clooney was no stranger there.

I don't remember who wins awards [Oscars]. I've won a few but what I really remember are movies. I love films, so I'm not concerned about speculation about winning things because I really enjoy being in films that last longer than an opening weekend. That's my goal in life.

Directing is much more satisfying to me than acting.

I'm always sort of optimistic about how good we are, as a country, at fixing ourselves.