After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

Life’s better with company. Everybody needs a co-pilot.

The owner of a local cannabis café told reporters George Clooney was no stranger there.

I can't give you 150 takes. I can't even give you 30 different ways of doing it! I don't have the talent or the range for it.

If you don't drink coffee, I am suspicious of your character and will not invite you to my Italian lake home.

I'm a liberal. I'm confused when that became a bad word...

Over the course of my career, I've had the great fortune of working with some incredible filmmakers who have protected me and inspired me and taught me what an honor it is to work in film.