I don't believe in happy endings, but I do believe in happy travels, because ultimately, you die at a very young age, or you live long enough to watch your friends die. It's a mean thing, life.

You learn from the mistakes you make and from the mistakes other people make. The truth is, you don't learn from success; you learn from failure.

The loneliest you will get is in the most public of arenas: You will go to a place and end up in the smallest compartment possible, because it's a distraction to everybody, and you end up not getting to enjoy it like everyone else.

After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

Look, it's very easy to sit here right now with some films in the bank that I like and think I have a shot and feel pretty cocky. But, you know, three years from now, I could very easily be saying, 'Paper or plastic?'

I just think there are a lot of celebrities who don't feel that they have a voice. A lot of actors come from a place of fear, and that's just a general statement about actors. You're terrified the casting director won't like you, you're terrified the producer won't like you, you're terrified the director won't like you, and on and on.

Never get behind old people. Their bodies are littered with hidden metal and they never seem to appreciate how little time they have left