When you're young, you tend to believe what people tell you, and that's dangerous. As you get older, you learn that you're never as good or as bad as they say you are. If you understand this, you win.

For me the definition of a patriot is someone who is willing to constantly question the government; that’s what separates us from other countries.

After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

It's not about an opening weekend. It's about a career, building a set of films you're proud of. Period.

The best advice I got from my aunt, the great singer Rosemary Clooney, and from my dad, who was a game show host and news anchor, was: don't wake up at seventy years old sighing over what you should have tried. Just do it, be willing to fail, and at least you gave it a shot. That's echoed for me all through the last few years.

Acting is one element in a film. Directing is sort of the painter using all of those elements - sound and music and camera and putting it all together. And that can be fun and exciting. If you fail, it's incredibly upsetting - much more upsetting than when you're an actor. But when you succeed it's incredibly, incredibly exciting, so I like the risk of it all.

The owner of a local cannabis café told reporters George Clooney was no stranger there.