In Oceania at the present day, Science, in the old sense, has almost ceased to exist. In Newspeak there is no word for 'Science.' The empirical method of thought, on which all the scientific achievements of the past were founded, is opposed to the most fundamental principles of Ingsoc.

The writers I care about most and never grow tired of are: Shakespeare, Swift, Fielding, Dickens, Charles Reade, Flaubert and, among modern writers, James Joyce, T. S. Eliot and D. H. Lawrence. But I believe the modern writer who has influenced me most is Somerset Maugham, whom I admire immensely for his power of telling a story straightforwardly and without frills.

So long as they (the Proles) continued to work and breed, their other activities were without importance. Left to themselves, like cattle turned loose upon the plains of Argentina, they had reverted to a style of life that appeared to be natural to them, a sort of ancestral pattern...Heavy physical work, the care of home and children, petty quarrels with neighbors, films, football, beer and above all, gambling filled up the horizon of their minds. To keep them in control was not difficult.

Manchester is the belly and guts of the nation

But what is work and what is not work? Is it work to dig, to carpenter, to plant trees, to fell trees, to ride, to fish, to hunt, to feed chickens, to play the piano, to take photographs, to build a house, to cook, to sew, to trim hats, to mend motor bicycles? All of these things are work to somebody, and all of them are play to somebody. There are in fact very few activities which cannot be classed either as work or play according as you choose to regard them.

...every human being is doomed to die, which is the greatest of all failures.

Doublethink means the power of holding two contradictory beliefs in one's mind simultaneously, and accepting both of them.