I wasn't sure what I wanted to do with my life. I always wanted to pursue either music or comics, so when the opportunity came from comics publisher Fantagraphics for my brothers Jaime and Mario and I to make a comic book together, we jumped at the chance: "Let's just do it and see what happens." Really, we weren't sure where we were going to go with it. We thought our work was good enough to be out there, but we didn't know that the response was going to be pretty good, pretty quick.

I felt like challenging myself and challenging my readers with something darker and heavier. I don't know how to explain it, because I'm not a political person. I have two political stories, and that's it: 'Human Diastrophism' and 'Poison River'.

I've always been interested in the way males seem to need to start clubs, or cults, to keep girls out until they need them for sex. It comes from some weird immature tribal crap, I'm sure.

It wasn't until I started to do 'Poison River' that the readership started falling. 'Poison River' started out very slowly and simply, but then it got really dense and complicated. I don't know, I think the readers just got fed up or burned out. They started dropping off.

I've dealt with Hollywood about having my work made into a film or cartoon but nothing came of it. That's not to say I wouldn't like to see something happen.

If you believe in what you're doing, and someone criticizes that, it's likely that they're just coming from a different place and they're bringing their own baggage and it's basically projection. I try not to let it get to me.

I had always shown childhood as something difficult, something you want to get the hell out of, but now I wanted to do a story that was the opposite, about that moment in time when you're in that world of discovery, doing what you want to do. That fleeting moment when you're in your zone.