When you're playing a man, you can look tired and horrible and you still look okay. As a woman, if you're tired, it's terrible. It was such a luxury not having to worry about that.

Be aware of your inner voice and follow it, even though most of the time it will tell you the most uncomfortable path to choose.

People think that the ocean is big enough to sustain anything we throw at it - its hard to get into your head that it's actually finite.

The mentally ill frighten and embarrass us. And so we marginalize the people who most need our acceptance. What mental health needs is more sunlight, more candor, more unashamed conversation.

I love the chemistry that can be created onstage between the actors and the audience. It's molecular even, the energies that can go back and forth. I started in theater and when I first went into movies I felt that my energy was going to blow out the camera.

The best thing I have is the knife from Fatal Attraction. I hung it in my kitchen. It's my way of saying, Don't mess with me.

So I think things are going to get closer and closer to each other, because the screens will force that to happen. I think there are a lot of movies that people will only see on their computers or their iPods.