Never again will I allow our political self-interest to deter us from doing what we know to be morally right. Atrocity and terror are not political weapons. And to those who would use them, your day is over. We will never negotiate. We will no longer tolerate and we will no longer be afraid. It's your turn to be afraid.

Hokey religions and ancient weapons are no match for a good blaster at your side, kid.

Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

Irish as a person but I feel Jewish as an actor.

I think what a lot of action movies lose these days, especially the ones that deal with fantasy, is you stop caring at some point because you've lost human scale.

A bad guy in a movie has a lot of latitude for acting. He can walk up the wall, crawl across the ceiling, go piss in the corner and everybody will say, "Fantastic!" But somebody's going to have to catch that sucker. Somebody's going to have to play the guy who gets him in the end. And that's a better part.

There have been times in my life when I have felt I was lonely, but I don't think you want to live your life in order to mitigate against loneliness.