I just like the process of taking something written on a sheet of paper and giving it life and shape. I like the collaborative process of filmmaking, which is all simply to say that I love my work and I would continue to look for things that have the potential to be engaging and successful.

I was completely unprepared for the public spectacle my private life became, and didn't like it a bit.

Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

I am not the first man who wanted to make changes in his life at 60 and I won't be the last. It is just that others can do it with anonymity.

Behind every great man is a woman. Telling him he's not so hot.

What I found was an emotional consistency with him. The words, the scenes, the situations - I wasn't mimicking what I thought Branch Rickey's emotional reality would have been.

You have to have the darkness for the dawn to come.