You have to have the darkness for the dawn to come.

Parenting is an impossible job at any age.

I could take Sean Connery in a fight... I could definitely take him.

It doesn't matter to me whether I go back to outer space or not [while acting]. The job's the same and I don't have any sort of genre preferences. I'm looking for a good story and a good character, whether earthbound or not.

Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

I try to preserve a certain amount of time away from the movies, so I don't allow time to do those smaller parts that might give me an opportunity to do more seemingly 'artful' things. Although, having said that, I don't feel any lack of noble purpose if I do a film that's commercial.

I do not go to the gym. I do not train. I am not that careful about what I eat. I cannot give you any advice about keeping fit. The best advice I can give is choose your parents wisely.