The test of science is not whether you are reasonable—there would not be much of physics if that was the case—the test is whether it works. And the great point about Newton’s theory of gravitation was that it worked, that you could actually say something about the motion of the moon without knowing very much about the constitution of the Earth.

What I remember most clearly was that when I put down a suggestion that seemed to me cogent and reasonable, Einstein did not in the least contest this, but he only said, 'Oh, how ugly.' As soon as an equation seemed to him to be ugly, he really rather lost interest in it and could not understand why somebody else was willing to spend much time on it. He was quite convinced that beauty was a guiding principle in the search for important results in theoretical physics.

The scientist … must always be prepared to deal with the unknown. It is an essential part of science that you should be able to describe matters in a way where you can say something without knowing everything.

An observer situated in a nebula and moving with the nebula will observe the same properties of the universe as any other similarly situated observer at any time.

The true contrast between science and religion is that science unites the world and makes it possible for people of widely differing backgrounds to work together and to cooperate. Religion, on the other hand, by its very claim to know “The Truth” through “revelation,” is inherently divisive and a creator of separatism and hostility.

The landscape has been so totally changed, the ways of thinking have been so deeply affected, that it is very hard to get hold of what it was like before… It is very hard to realize how total a change in outlook Isaac Newton has produced.

A theory is scientific only if it can be disproved. But the moment you try to cover absolutely everything the chances are that you cover nothing.