I feel like I have to do the best job I can to basically say, "OK, I understand - you have every right to be angry, but anger is not a plan. Here's what I want to do, and that's why I hope you will support me, because I think it will actually improve the lives of Americans."

[Iranians] are destabilizing governments in the region. They continue to support Hezbollah and Hamas in Lebanon against Israel. A lot of work that we have do is going to be incredibly hard. I'm prepared to do that work, but I believe, just as I did with imposing the sanctions, you have to get action for action.

From my perspective it matters what we do, not what we say. It mattered that we got Bin Laden, not the name we called him.

I think what President [Barack] Obama has done is to chart a steady course. When I was there, the first four years we had a lot of cleanup to do. We inherited a lot of bad feelings from the [George W.] Bush administration, and much of what I spent my time doing was traveling around the world reassuring friends and allies.

We don't think about women being leaders.

Now, I know there are many Americans who say, 'Get out of Afghanistan. Bring 'em all home.' And there are others who say, 'Put in hundreds of thousands of more.'

I think it's important for people to say look, what does each party and each candidate have to offer for you. If you want a better future that is going to be reliant on making smart economic policies, compare my husband's eight years with Ronald Reagan's eight years. 23 million new jobs, more than seven million people lifted out of poverty.