It is changes that are chiefly responsible for diseases, especially the greatest changes, the violent alterations both in the seasons and in other things. (:)...regimen and temperature, and one period of life to another.
HippocratesWe must turn to nature itself, to the observations of the body in health and in disease to learn the truth.
HippocratesAll parts of the body which have a function, if used in moderation and exercised in labors in which each is accustomed, become thereby healthy, well developed and age more slowly, but if unused they become liable to disease, defective in growth and age quickly.
Hippocrates