If we study Nature attentively in its great evolutions as in its minutest works, we cannot fail to recognize the possibility of enchantment - giving to that word its exact significance.
Honore de BalzacIt is beyond a doubt that during the sixteenth century, and the years immediately preceding and following it, poisoning had been brought to a pitch of perfection which remains unknown to modern chemistry, but which is indisputably proved by history. Italy, the cradle of modern science, was at that time, the inventor and mistress of these secrets, many of which are lost.
Honore de Balzac