Driving a motorcycle is like flying. All your senses are alive. Being House is like flying, too. He's free of the gravity of what people think.

I have a reverence for medicine because I hero-worshiped my father [a former doctor], and because I admire doctors, I admire study, empiricism and rational thought. I don't study, empiricize or think rationally myself - but I admire it in others.

Acting is largely about putting on masks, and music is about removing them.

My dad gave me my first bike at 16. I soon fell off and was in a wheelchair for weeks. I haven't fallen since.

I remember watching Mel Gibson on some show once, and he was being asked about his belief in the afterlife. Gibson said: 'Well, I can't believe this is all there is'. And I thought: 'Wait a minute. You're Mel Gibson. You have millions of dollars. You're a great-looking chap with every conceivable blessing that could be bestowed upon a man. And that's not good enough ?'

I was shown into a room. A red room. Red wallpaper, red curtains, red carpet. They said it was a sitting-room, but I don’t know why they’d decided to confine its purpose just to sitting. Obviously, sitting was one of the things you could do in a room this size; but you could also stage operas, hold cycling races, and have an absolutely cracking game of frisbee, all at the same time, without having to move any of the furniture. It could rain in a room this big.

I rowed for Cambridge. I was pretty good at that.