Happiness is the twinkle in your grandmother's eye as you reverse the tractor off her legs.

To be able to pretend to be something that I'm frankly not is very liberating and exciting.

I don't talk like House, or walk like him. I certainly don't think like him. I don't like to think for more than 15 minutes at a stretch actually; I am a fragile flower.

LA runs on optimism, enthusiasm and flattery. I think you can go a little bit crazy... It's just too damn sunny in every dimension - weatherwise, socially and professionally.

It is the middle of December now, and we are about to travel to Switzerland - where we plan to ski a little, relax a little, and shoot a Dutch politician a little.

I have a reverence for medicine because I hero-worshiped my father [a former doctor], and because I admire doctors, I admire study, empiricism and rational thought. I don't study, empiricize or think rationally myself - but I admire it in others.

This was the tricky bit. The really tricky bit, trickiness cubed.