Science is a set of rules to keep us from telling lies to each other. All scientists really have is a reputation for telling the truth.

And it came to pass that AC learned how to reverse the direction of entropy. But there was now no man to whom AC might give the answer of the last question. No matter. The answer - by demonstration - would take care of that, too. For another timeless interval, AC thought how best to do this. Carefully, AC organized the program. The consciousness of AC encompassed all of what had been a Universe and brooded over what was now Chaos. Step by step, it must be done. And AC said, "LET THERE BE LIGHT!" And there was light...

The energy requirements for interstellar travel are so great that it is inconceivable to me that any creatures piloting their ships across the vast depths of space would do so only in order to play games with us over a period of decades. If they want to make contact, they would make contact; if not, they would save their energy and go elsewhere.

Was there anything more exciting in life than seeking answers?

Science is dangerous. There is no question but that poison gas, genetic engineering, and nuclear weapons and power stations are terrifying. It may be that civilization is falling apart and the world we know is coming to an end. In that case, why no turn to religion and look forward to the Day of Judgment, ... [being] lifted into eternal bliss ... [and] watching the scoffers and disbelievers writhe forever in torment.

When I feel difficulty coming on, I switch to another book I'm writing. When I get back to the problem, my unconscious has solved it.

If a conclusion is not poetically balanced, it cannot be scientifically true.