All knowledge and understanding of the Universe was no more than playing with stones and shells on the seashore of the vast imponderable ocean of truth.

Physics, beware of metaphysics.

His epitaph: Who, by vigor of mind almost divine, the motions and figures of the planets, the paths of comets, and the tides of the seas first demonstrated.

The way to chastity is not to struggle directly with incontinent thoughts but to avert the thoughts by some imployment, or by reading, or meditating on other things.

If I had stayed for other people to make my tools and things for me, I had never made anything.

Therefore to the same natural effects we must, as far as possible, assign the same causes.

What we know is a drop, what we don't know is an ocean.