The older I get, the more I believe that at the bottom of most deep mathematical problems there is a combinatorial problem.
Israel Gelfand... The approach of von Neumann and Connes to the use of non-commutative algebra in physics is naive, the situation is much more complicated.
Israel GelfandEugene Wigner wrote a famous essay on the unreasonable effectiveness of mathematics in natural sciences. He meant physics, of course. There is only one thing which is more unreasonable than the unreasonable effectiveness of mathematics in physics, and this is the unreasonable ineffectiveness of mathematics in biology.
Israel Gelfand