Science now finds itself in paradoxical strife with society: admired but mistrusted; offering hope for the future but creating ambiguous choice; richly supported yet unable to fulfill all its promise; boasting remarkable advances but criticized for not serving more directly the goals of society.

I wrote a letter to Harvard, explaining that I was having difficulty deciding between it and the University of Pennsylvania. Could I come and visit? Years later, the dean of students at Harvard told me that my letter had been posted in the dean’s office for the amusement of the staff. Thus did I learn the measure of institutional arrogance.

Science now finds itself in paradoxical strife with society: admired but mistrusted; offering hope for the future but creating ambiguous choice; richly supported yet unable to fulfill all its promise; boasting remarkable advances but criticized for not serving more directly the goals of society.

The modern research laboratory can be a large and complicated social organism.