'It worked.' (said after witnessing the first atomic detonation).

There must be no barriers for freedom of inquiry... There is no place for dogma in science. The scientist is free, and must be free to ask any question, to doubt any assertion, to seek for any evidence, to correct any errors.

We may anticipate a state of affairs in which two Great Powers will each be in a position to put an end to the civilization and life of the other, though not without risking its own. We may be likened to two scorpions in a bottle, each capable of killing the other, but only at the risk of his own life.

To the confusion of our enemies.

Science starts with preconception, with the common culture, and with common sense. It moves on to observation, is marked by the discovery of paradox, and is then concerned with the correction of preconception. It moves then to use these corrections for the designing of further observation and for more refined experiment. And as it moves along this course the nature of the evidence and experience that nourish it becomes more and more unfamiliar; it is not just the language that is strange [to common culture].

A pragmatist is concerned with results, not reality.

Both the man of science and the man of art live always at the edge of mystery, surrounded by it. Both, as a measure of their creation, have always had to do with the harmonization of what is new with what is familiar, with the balance between novelty and synthesis, with the struggle to make partial order in total chaos.... This cannot be an easy life.