The most remarkable discovery made by scientists is science itself. The discovery must be compared in importance with the invention of cave-painting and of writing. Like these earlier human creations, science is an attempt to control our surroundings by entering into them and understanding them from inside. And like them, science has surely made a critical step in human development which cannot be reversed. We cannot conceive a future society without science.

When Da Vinci wanted an effect, he willed, he planned the means to make it happen: that was the purpose of his machines. But the machines of Newton ... are means not for doing but for observing. He saw an effect, and he looked for its cause.

Fifty years from now if an understanding of man's origins, his evolution, his history, his progress is not in the common place of the school books we shall not exist.

It is a mistake to think of creative activity as something unusual

The discoveries of science, the works of art are explorations - more, are explosions, of a hidden likeness. The discoverer or artist presents in them two aspects of nature and fuses them into one. This is the act of creation, in which an original thought is born, and it is the same act in original science and original art.

I grew up to be indifferent to the distinction between literature and science, which in my teens were simply two languages for experience that I learned together.

[John] Dalton was a man of regular habits. For fifty-seven years he walked out of Manchester every day; he measured the rainfall, the temperature-a singularly monotonous enterprise in this climate. Of all that mass of data, nothing whatever came. But of the one searching, almost childlike question about the weights that enter the construction of these simple molecules-out of that came modern atomic theory. That is the essence of science: ask an impertinent question, and you are on the way to the pertinent answer.