Man is a singular creature. He has a set of gifts which make him unique among the animals, so that unlike them, he is not a figure in the landscape, he is the shaper of the landscape.

Dissent is the mark of freedom, as originality is the mark of independence of mind. … No one can be a scientist … if he does not have independence of observation and of thought.

Progress is the exploration of our own error. Evolution is a consolidation of what have always begun as errors. And errors are of two kinds: errors that turn out to be true and errors that turn out to be false (which are most of them). But they both have the same character of being an imaginative speculation. I say all this because I want very much to talk about the human side of discovery and progress, and it seems to me terribly important to say this in an age in which most non-scientists are feeling a kind of loss of nerve.

The values by which we are to survive are not rules for just and unjust conduct, but are those deeper illuminations in whose light justice and injustice, good and evil, means and ends are seen in fearful sharpness of outline.

Knowledge is not a loose leaf notebook of facts.

But nature - that is, biological evolution - has not fitted man to any specific environment. On the contrary, ... he has a rather crude survival kit; and yet -this is the paradox of the human condition - one that fits him to all environments. Among the multitude of animals which scamper, fly, burrow and swim around us, man is the only one who is not locked into his environment. His imagination, his reason, his emotional subtlety and toughness, make it possible for him not to accept the environment but to change it.

Ask an impertinent question and you are on the way to the pertinent answer.