Peer reviewers go for orthodoxy ... Many of the great 19th-century discoveries were made by men who had independent wealth-Charles Darwin is the prototype. They trusted themselves.

[There is no shortage of scientific talent.] But [I am] much less optimistic about the managerial vision [of the pharmaceutical industry] to catalyse these talents to deliver the results we all want.

Peer reviewers go for orthodoxy ... Many of the great 19th-century discoveries were made by men who had independent wealth-Charles Darwin is the prototype. They trusted themselves.

The techniques have galloped ahead of the concepts. We have moved away from studying the complexity of the organism; from processes and organisation to composition.

I learnt, for the first time, the joys of substituting hard, disciplined study for the indulgence of day-dreaming.

Apart from two periods of intense study, of music between the ages of 12 and 14 and of mathematics between the ages of 14 and 16, I coasted, daydreaming, through most of my school years.

I did help to set up an undergraduate course in medicinal chemistry and made progress in modelling and analysing pharmacological activity at the tissue level, my new passion.