The survival rate of Dr Burton's patients approximately doubled the maximum survival rate of conventionally treated patients. Had these findings pertained to a chemotherapy drug instead of IAT, massive amounts of funding would have been allocated to investigate the drug. Once again, the politics of cancer barred a potentially valuable treatment from reaching the public.

Two types of choices seem to me to have been crucial in tipping the outcomes [of the various societies' histories] towards success or failure: long-term planning and willingness to reconsider core values. On reflection we can also recognize the crucial role of these same two choices for the outcomes of our individual lives.

Forced to choose between limiting population or trying to increase food production, we chose the latter and ended up with starvation, warfare, and tyranny.

Bird taxonomy is a difficult field because of the severe anatomical constraints imposed by flight. There are only so many ways to design a bird capable, say, of catching insects in mid-air, with the result that birds of similar habitats tend to have very similar anatomies, whatever their ancestry. For example, American vultures look and behave much like Old World vultures, but biologists have come to realize that the former are related to storks, the latter to hawks, and that their resemblances result from their common lifestyle.

But this was the only way of life that humans knew for their first 6m years on the planet. In giving it up over the past few thousand years, we have lost our vulnerability to disease and cold and wild animals, but we have also lost good ways to bring up children, look after old people, stave off diabetes and heart disease and understand the real dangers of everyday life.

Perhaps our greatest distinction as a species is our capacity, unique among animals, to make counter-evolutionary choices.

The Anasazi did manage to construct in stone the largest and tallest buildings erected in North America until the Chicago steel girder skyscrapers of the 1880s.