This whole thing about winning and losing is muddy waters. But I can remember, as a young actor, just walking around this city and not being able to get arrested.

Guillermo del Toro. He's in his pure artist's stroke. He's just hitting it out of the park. I would go anywhere to work with him. He's a real artist.

The most telling one was recently on a plane. This guy very dressed up and formal - the watch, the shoes, the cufflinks, the whole nine yards - he came at me, and I thought I was going to get nailed. But he literally came up to me and just gave me a hug and said, "Thank you for introducing me to a subject that I didn't know anything about." In those moments it always clicks for me what we're doing here.

I get a singular comment that's very revealing: "I didn't know what to expect." Every time I hear that I think it's really just code for, "I wasn't sure I'd be comfortable with you in this role," which I understand coming from Oscar Bluth and Hank Kingsley and whatever. But I think there's a degree of, "Oh, okay, this is how it is." Then almost always people tell me that they love it and then people start talking to me about their families, whether it's transgender issues or not.

You keep your head down and you work and work, and all of a sudden you pick your head up and people are receiving it the same way we're sending it. They're thinking the same things that I'm thinking about the show.

The Larry Sanders Show сhanged my life. I am so thankful that - I mean, go figure. Most people are lucky to get one good series, but I got two ground-breakers. I just knew when I read that "Hey Now" script that something was afoot. Those were seven of the greatest years of my life. I learned so much, and it affirmed everything I thought comedy was. It was really a tremendous experience.

Carlos Castaneda always said, "If you're going to do something, do it impeccably."