Biology has tended to be an observational science and deriving things from first principles has not been possible in the past but I hate to predict the future on that.

If you take a galaxy and try to make it bigger, it becomes a cluster of galaxies, not a galaxy. If you try to make it smaller than that, it seems to blow itself apart.

The discrepancy between what was expected and what has been observed has grown over the years, and we're straining harder and harder to fill the gap.

There's no observational evidence that I know of that indicates electric and magnetic forces are important on cosmological scales.

There are reasons, increasing in number and quality, to believe that the masses of ordinary galaxies may have been underestimated by a factor of 10 or more.

Biology has tended to be an observational science and deriving things from first principles has not been possible in the past but I hate to predict the future on that.