America's leaders have to find a way to work together, rise to the challenge, and come up with solutions as bold and visionary as the people of this nation.

The Constitution says the President shall nominate, not maybe he could, maybe he can't, he shall nominate. Implicit in the Constitution is that the Senate will act on its constitutional responsibility and give its advice and consent. No one is required to vote for the nominee.

One of the reasons to pick the cancer effort is to demonstrate to people that there's not much beyond our capacity. It will take time, but if we focus, if we narrow down where the bottle necks are and we move, there's never been a problem we can't solve.

Folks, I can tell you I've known eight presidents, three of them intimately.

There's about 100 different cancers in a cancer cell. And so what we're finding out is, they're finding out ways to deal with one or two of the cancers there, with certain medicines. But they don't know why, if you have that cancer and I have that cancer, and I get the therapy and you get it, I don't live and you live. That - they don't know why.

The public has moved beyond politicians. For example, I'm not worried about them repealing protections for the LGBT community, because the public is beyond that. I'm not worried about them being able to change the way in which we have reached out and provided many more opportunities for women. And I - but here's what does concern me. What concerns me is that they will make some judgments in the foreign policy area, without having thought it through that may cause a lot of problems.

I always kid the president in different circumstances. Mr. President, a country's never going to be more optimistic than the president.