In 1920 [H.G. Wells] described human history as becoming more and more a race between education and catastrophe.

There are three levels of happiness: the pleasant life, the good life, and the meaningful life.

If you put a large switch in some cave somewhere, and a sign on it saying, "End-of-the-World Switch. PLEASE TO NOT TOUCH," the paint wouldn't even have time to dry.

Transcendence is the only real alternative to extinction. This is serious. This may be the ultimate final exam.

The physician who waits until dead certain of a diagnosis before acting is likely to wind up with a dead patient. Sometimes things develop so rapidly that only early action-back when you're still somewhat uncertain-stands a chance of being effective, as in catching cancer before it metastasizes.

The next frontier is our own selves.

We are at an inflection point in history.