...Cities may be rebuilt, and a People reduced to Poverty, may acquire fresh Property: But a Constitution of Government once changed from Freedom, can never be restored. Liberty once lost is lost forever. When the People once surrendered their share in the Legislature, and their Right of defending the Limitations upon the Government, and of resisting every Encroachment upon them, they can never regain it.

I request that they may be considered in confidence, until the members of Congress are fully possessed of their contents, and shall have had opportunity to deliberate on the consequences of their publication; after which time, I submit them to your wisdom.

There are persons whom in my heart I despise, others I abhor. Yet I am not obliged to inform the one of my contempt, nor the other of my detestation. This kind of dissimulation...is a necessary branch of wisdom, and so far from being immoral...that it is a duty and a virtue.

Before any great things are accomplished, a memorable change must be made in the system of education...to raise the lower ranks of society nearer to the higher.

When legislature is corrupted, the people are undone.

My History of the Jesuits is in four volumes.... This society has been a greater calamity to mankind than the French Revolution, or Napoleon's despotism or ideology. It has obstructed progress of reformation and the improvement of the human mind in society much longer and more fatally.

Negro Slavery is an evil of Colossal magnitude. I am therefore utterly averse to the admission of Slavery into the Missouri Territory, and heartily wish that every Constitutional measure may be adopted for the preservation of it.