For a while I had a blues band in L.A., but I realized I was too optimistic to play the blues. I did not have the misery in my heart that the blues required.

When I first joined SAG, there was another John Reilly. My dad was John Reilly, too, but growing up I was John John. Nobody in life calls me John C. It's more like, "Hey you, Step Brother!"

Here's the thing, with comedy - and I learned this from Will Ferrell - you can't be ashamed. If you're doing comedy, you have to fully commit to the joke. Shame is not part of it. If you act shy or uncomfortable about your body, that makes the audience shy and uncomfortable. And in a comedy you just want them to loosen up and laugh.

I don't think I could ever stop doing serious movies and just do comedies, or vice versa, but there is something cool about going to work everyday and you're just trying to make your friends laugh. That's nice work if you can get it, you know what I mean? It's different than going to work and knowing that I've gotta slap someone in the face today, and then I've gotta cry, and someone's gonna die, I've gotta get myself to that place.

A lot of people that make films say, 'We need this kind of character. Who's done it before? Get them to do it again.' That is exactly what actors are pushing against. It's kind of a cliche to talk about being stereotyped in that way, but it happens.

For a long time, it was like I was part of some special forces unit: I'd land, meet everyone, five minutes later I'd have to do some amazing work, then - boom! - I'm out again. You know, playing supporting parts takes courage.

I view my strongest competition as myself. You're always trying to top yourself, rather than worrying about what other people are doing.