Whenever I work on something, I try and throw everything I have at it. Then if the director finds it useful they use it, and if not, they ignore it!

If you're really being honest with yourself when you're acting, part of it is touching the real you. You can only separate yourself so much from the character. Those vulnerable moments do touch me.

The way you get through having a shitty job is to laugh a lot and goof around.

Here's the thing, with comedy - and I learned this from Will Ferrell - you can't be ashamed. If you're doing comedy, you have to fully commit to the joke. Shame is not part of it. If you act shy or uncomfortable about your body, that makes the audience shy and uncomfortable. And in a comedy you just want them to loosen up and laugh.

When I first joined SAG, there was another John Reilly. My dad was John Reilly, too, but growing up I was John John. Nobody in life calls me John C. It's more like, "Hey you, Step Brother!"

I've never been someone who's been given work because of the way I look or because I have some box office appeal. I get work because people know I'm swinging as hard as I can, trying to connect, giving it my level best. I have a face for radio, but here I am doing what I do.

You know, the truth is that us actors would all like to believe we re-invent the wheel, every time we play a character. But, we're human beings and our instruments are not violins, they are our bodies and our consciousness and our collective life experience.