We're going to be focusing our science on things that will take us farther and longer into space. For many of those experiments, the crew members are human guinea pigs, which is fine; that's part of my job. I don't mind being a human guinea pig.

We would like to carry out 100 percent, or maybe more, of our scientific program; I would like to devote some of my spare time toward extra scientific work.

If I wasn't doing this kind of exploration, I'd like to be doing some other kind of exploration. It might be more risky, or less risky, but, in the business of exploration, risk is part of the territory.

It took me a long time to get selected as an astronaut. In fact, I applied for 20 years before I was selected.

Researchers can measure what kind of angles your legs take up during the day when they're just trailing around behind you in weightless conditions, and what kind of impacts you feel during your exercise. They're going to compare that with what we do on the ground.

The Space Shuttle will stop directly below the Space Station and Sergei and I will be looking out two different windows looking straight down at the Space Shuttle.

Even with only two people on board, where maintenance is a large piece of our working day, we still have time to do scientific research. We have to be ready to support those Shuttle visits in a lot of different ways.