Revolt is the right of the people

Though the familiar use of things about us take off our wonder, yet it cures not our ignorance.

When we know our own strength, we shall the better know what to undertake with hopes of success.

The Commonwealth of Learning is not at this time without Master-Builders, whose mighty Designs, in advancing the Sciences, will leave lasting Monuments to the Admiration of Posterity; But every one must not hope to be a Boyle, or a Sydenham; and in an Age that produces such Masters, as the Great-Huygenius, and the incomparable Mr. Newton, with some other of that Strain; 'tis Ambition enough to be employed as an Under-Labourer in clearing Ground a little, and removing some of the Rubbish, that lies in the way to Knowledge.

Many a good poetic vein is buried under a trade, and never produces any thing for want of improvement.

If you punish him for what he sees you practise yourself, he... will be apt to interpret it the peevishness and arbitrary imperiousness of a father, who, without any ground for it, would deny his son the liberty and pleasure he takes himself.

In my opinion, understanding who your target audience is, and what they want, and writing to them (and only them!) is the most important component of being successful as an author.