I wanted to write a book that imagined where advances in the study of genetics might lead us. Holman was the first character who came to me: I envisaged the misshapen offspring of beautiful, wealthy parents. Then I realised that he bore a striking resemblance to Toulouse-Lautrec. I developed that, made Holman an alcoholic who lives among hookers, an artist tortured by his disability.

New technologies are a good thing but we must consider how they will impact on us so that, when they become achievable, they aren't allowed to run amok.

At the moment we seem to be heading in the opposite direction. However you dress it up, it's pretty obvious who is being affected by the government's cuts.

Social mobility decreased under Labour and under the current government it is reversing. The differences between the poorest and richest are returning to Victorian levels. We don't have open sewers and infant mortality rates at fifty percent but in economic terms we're getting to a level of disparity we haven't seen for a couple of hundred years. And we're getting there very quickly.

I'm slightly pessimistic about human nature, about how close it's possible to bond with those around you. Dying alone is a deep fear for most people. I'm not scared of death but I'm scared of dying scared. Maybe everything else in life comes from those two points: the separation anxiety of childhood and the ultimate fear of dying alone.

There are very good evolutionary reasons for having religion. From early human history we have evolved a need to see God. We have a perception of ourselves and in order for that to be a true perception we have to believe in a soul within us.

I do always know where I'm going in my books. I know the endpoint. I've written only two thousand words of my next novel but I know what the ending will be already.