This is the reality of nuclear weapons: they may trigger a world war; a war which, unlike previous ones, destroys all of civilization.

But the first the general public learned about the discovery was the news of the destruction of Hiroshima by the atom bomb. A splendid achievement of science and technology had turned malign. Science became identified with death and destruction.

Technology is driving us together. In many ways we are becoming like one family. With the global threats resulting from science and technology, the whole of humankind now needs protection. We have to extend our loyalty to the whole of the human race.

The present basic philosophy is nuclear deterrence.

So I ask the nuclear powers to abandon the out-of-date thinking of the Cold War period and take a fresh look. Above all, I appeal to them to bear in mind the long-term threat that nuclear weapons pose to humankind and to begin action towards their elimination.

At a time when science plays such a powerful role in the life of society, when the destiny of the whole of mankind may hinge on the results of scientific research, it is incumbent on all scientists to be fully conscious of that role, and conduct themselves accordingly.

I did not imagine that the second half of my life would be spent on efforts to avert a mortal danger to humanity created by science.