The Americas has been a relatively stable continent. The last truly new border we have is Panama in 1903.

There are certain zip codes that generate a disproportionate share of patents, of startups, of wealth, of jobs. And it's really important if other parts of the country are going to want to create these tech centers.

It's actually very hard to find an area of the economy that doesn't fundamentally change in the measure that we are able to read and write life code.

If you had a front row seat at the Renaissance, you would have seen Machiavelli come by plotting, and you would have seen murders in the streets, you would have seen violence, you have seen people burning books and it would have looked like the world was a horrible place, but that's where all these incredible stuff we're still living with comes out of.

If you don't have that science and technology and brains as an input, as you don't have in large parts of Latin America, if you don't focus your education on that, if you don't find your 10,000 best scientists, but you do find your 10,000 best soccer players, the consequences are, you become a World Cup Champion in Soccer, like Brazil, but you don't become Korea, which earned 1/5 of what a Mexican did in 1975 and today earns five times more.

I've always been interested in why countries appear and disappear. And the curious thing is how often it happens.

There's always a question when you invest. Are you too early, are you too late, or are you just right? And there was a lot of hype about life sciences, around the sequencing of the human genome and a lot of people concluded that's not really there. But by the way, there was a lot of hype around the digital revolution just about the time of 2000 and the human genome, and it turns out that some of the world's biggest, most powerful companies are the survivors post that crash.