It's actually very hard to find an area of the economy that doesn't fundamentally change in the measure that we are able to read and write life code.

After a lot of debate and a lot of work, what people decided is, it makes a great deal of sense to be open in the system and allow people to begin to build better flu vaccines. I mean, we're still making them in eggs that come out of chickens. And we can see the consequences of that with the current H1N1 lack of vaccines.

Cities are magical things. You know the energy in them. You have to walk the streets in any borough here and you can see between what was in this city in the 1970's and where it is today and how much more energy there is and how much more just sheer.

It's such an extraordinary time to be alive that you just don't want to miss it. I mean, it's a really neat historical period.

There's always a question when you invest. Are you too early, are you too late, or are you just right? And there was a lot of hype about life sciences, around the sequencing of the human genome and a lot of people concluded that's not really there. But by the way, there was a lot of hype around the digital revolution just about the time of 2000 and the human genome, and it turns out that some of the world's biggest, most powerful companies are the survivors post that crash.

There's a creativity, a power, an energy, an ability to do things unlike any other period in history. It's a little bit like sitting in the Renaissance, but multiplied a thousand-fold.

As countries appear and disappear, then I began to ask, what makes countries successful? And it turns out, after a long slog through geographies and ethnicities and all kinds of variables, it's the ability to adapt and adopt, what Darwin talked about.