There's always a question when you invest. Are you too early, are you too late, or are you just right? And there was a lot of hype about life sciences, around the sequencing of the human genome and a lot of people concluded that's not really there. But by the way, there was a lot of hype around the digital revolution just about the time of 2000 and the human genome, and it turns out that some of the world's biggest, most powerful companies are the survivors post that crash.

The thing that's really important to understand is, the last thing an empire traditionally does is drive itself into bankruptcy. You've seen that with the great empires.

One of the things that really worries me, in part about Mexico, in part about Latin America, and in part about the Hispanic population in the U.S. and Canada. It's the lack of awareness of this whole science world.

Venture capital is about .02% of the U.S. economy invested, and it accounts for 11% of total U.S. jobs and 21% of U.S. economic output. And the reason why is because these companies can get very big, very quickly.

Try to live without something digital - without digital code for about two hours, very hard to do if you're awake.

People thought this was a computer IT gig, and that will flow through those nerdy departments and it won't come into fashion photography, it won't come into television, it won't come into my daily communications, it won't come into my telephone, my microphone, my light control, my microwave radio, my - I mean, just name it.

The housing crisis may not be the worst thing that's happened to New York City because it was becoming impossible for some of the young doctors, for some of the young artists, for some of the people that make the city so special to be able to live here.