I've come to believe that the simpler the title, the better. Whenever I try to get cute with it, it seems to be a problem but if it's just The 40-Year-Old Virgin, people seem to know what they're in for.

When I was very young, I started to make friends with much, much older people. So when I was twenty, my friends were fifty, and I never really went through forty because I would watch them die and I would feel younger. So you make friends with older people and you will always feel young no matter what.

To me, I've never understood why there is any question about are women as funny as men.

I always thought it was important to overdeliver, and when I got one of my first jobs, writing jokes for Garry Shandling when he was hosting the Grammys, I stayed up all night and wrote a hundred jokes, and I thought, "I'm always going to be the person that gives them more than they requested, and that's why they'll want to keep me around."

If everyone is mature, there is no comedy.

When you're making your 20th movie, it might be the 20th most incredible thing that's ever happened to you!

If you're an athlete, you might work your entire life, and you win the Super Bowl once, if you're lucky. And I feel like in the arts and entertainment we win the Super Bowl all the time.