I was bad at sports and picked last every day. I couldn't quite figure out what my role was in the social order, so I decided I was interested in comedy. And what was then interesting was, nobody else was interested in it at all. I didn't find one friend who was interested in comedy until I moved to California and met other comedians. And suddenly I knew hundreds of people who knew as much about SCTV as I did. But it took me 20 years to find those people.

Television is much more difficult because at every moment, the network can force you to change things based on their belief about what would make it popular. You’re in a constant debate with a gun to your head, and the gun is cancellation. So it’s hard to win the arguments.

When you're making your 20th movie, it might be the 20th most incredible thing that's ever happened to you!

I am always driven by the terror of humiliation.

I was a guest on Comedians in Cars Getting Coffee with Jerry Seinfeld, and I interviewed him when I was 15 years old-those moments really blow your mind.

I've made movies on every part of the spectrum, and you do understand when you go into certain movies that you're trying to elicit a certain kind of response from the audience, and people get a real sense of satisfaction when they're rooting for a character and the character pulls it off.

Right when I started getting solid was when I was offered a lot of writing work. And when The Ben Stiller Show was picked up, I realized there was no way for me to do stand-up three or four nights a week and run this television show with Ben. So that was the moment when I had to make a choice.