The metaphysical doctrine of determinism simply asserts that all events in this world are fixed, or unalterable, or predetermined. It does not assert that they are known to anybody, or predictable by scientific means. But it asserts that the future is as little changeable as is the past. Everybody knows what we mean when we say that the past cannot be changed. It is in precisely the same sense that the future cannot be changed, according to metaphysical determinism.
Karl PopperNature consists of facts and of regularities, and is in itself neither moral nor immoral. It is we who impose our standards upon nature, and who in this way introduce morals into the natural world, in spite the fact that we are part of this world. We are products of nature, but nature has made us together with our power of altering the world, of foreseeing and of planning for the future, and of making far-reaching decisions for which we are morally responsible. Yet, responsibility, decisions, enter the world of nature only with us
Karl PopperIn so far as a scientific statement speaks about reality, it must be falsifiable; and in so far as it is not falsifiable, it does not speak about reality.
Karl Popper