All we can do is search for the falsity content in our best theory.

The history of science, like the history of all human ideas, is a history of irresponsible dreams, of obstinacy, and of error. But science is one of the very few human activities-perhaps the only one-in which errors are systematically criticized and fairly often, in time, corrected. This is why we can say that, in science, we often learn from our mistakes, and why we can speak clearly and sensibly about making progress there. In most other fields of human endeavour there is change, but rarely progress ... And in most fields we do not even know how to evaluate change.

We know a great deal, but our ignorance is sobering and boundless. With each step forward, with each problem which we solve, we not only discover new and unsolved problems, but we also discover that where we believed that we were standing on firm and safe ground, all things are, in truth, insecure and in a state of flux.

Every discovery contains an irrational element or a creative intuition.

Good tests kill flawed theories; we remain alive to guess again.

A system is empirical or scientific only if it is capable of being tested by experience. These considerations suggest that not the verifiability but the falsifiability of a system is to be taken as a criterion of demarcation... It must be possible for an empirical or scientific system to be refuted by experience.

Contrary to the outstanding work of art, outstanding theory is susceptible to improvements.