The history of science, like the history of all human ideas, is a history of irresponsible dreams, of obstinacy, and of error. But science is one of the very few human activities-perhaps the only one-in which errors are systematically criticized and fairly often, in time, corrected. This is why we can say that, in science, we often learn from our mistakes, and why we can speak clearly and sensibly about making progress there. In most other fields of human endeavour there is change, but rarely progress ... And in most fields we do not even know how to evaluate change.

Science is the century-old endeavour to bring together by means of systematic thought the perceptible phenomena of this world into as thorough-going an association as possible. To put it boldly, it is the attempt at a posterior reconstruction of existence by the process of conceptualization. Science can only ascertain what is, but not what should be, and outside of its domain value judgements of all kinds remain necessary.

The question is not how to get good people to rule; THE QUESTION IS: HOW TO STOP THE POWERFUL from doing as much damage as they can to us.

Piecemeal social engineering resembles physical engineering in regarding the ends as beyond the province of technology.

The growth of knowledge depends entirely upon disagreement.

We should realize that, if [Socrates] demanded that the wisest men should rule, he clearly stressed that he did not mean the learned men; in fact, he was skeptical of all professional learnedness, whether it was that of the philosophers or of the learned men of his own generation, the Sophists. The wisdom he meant was of a different kind. It was simply the realization: how little do I know! Those who did not know this, he taught, knew nothing at all. This is the true scientific spirit.

[The aim of science is] to explain what so far has taken to be an explicans, such as a law of nature. The task of empirical science constantly renews itself. We may go on forever, proceeding to explanations of a higher and higher universality.