Thus science must begin with myths, and with the criticism of myths; neither with the collection of observations, nor with the invention of experiments, but with the critical discussion of myths, and of magical techniques and practices.
Karl PopperNo particular theory may ever be regarded as absolutely certain.... No scientific theory is sacrosanct.
Karl PopperTo give a causal explanation of an event means to deduce a statement which describes it, using as premises of the deduction one or more universal laws, together with certain singular statements, the initial conditions ... We have thus two different kinds of statement, both of which are necessary ingredients of a complete causal explanation.
Karl PopperIn point of fact, no conclusive disproof of a theory can ever be produced; for it is always possible to say that the experimental results are not reliable or that the discrepancies which are asserted to exist between the experimental results and the theory are only apparent and that they will disappear with the advance of our understanding. If you insist on strict proof (or strict disproof) in the empirical sciences, you will never benefit from experience, and never learn from it how wrong you are.
Karl Popper