Science does not rest upon solid bedrock. The bold structure of its theories rises, as it were, above a swamp. It is like a building erected on piles. The piles are driven down from above into the swamp, but not down to any natural or 'given' base; and if we stop driving the piles deeper, it is not because we have reached firm ground. We simply stop when we are satisfied that the piles are firm enough to carry the structure, at least for the time being.
Karl PopperNo particular theory may ever be regarded as absolutely certain.... No scientific theory is sacrosanct.
Karl PopperTo give a causal explanation of an event means to deduce a statement which describes it, using as premises of the deduction one or more universal laws, together with certain singular statements, the initial conditions ... We have thus two different kinds of statement, both of which are necessary ingredients of a complete causal explanation.
Karl PopperWhy do I think that we, the intellectuals, are able to help? Simply because we, the intellectuals, have done the most terrible harm for thousands of years. Mass murder in the name of an idea, a doctrine, a theory, a religion - that is all "our" doing, "our" invention: the invention of the intellectuals. If only we would stop setting man against man - often with the best intentions - much would be gained. Nobody can say that it is impossible for us to stop doing this.
Karl PopperIt is easy to obtain confirmations, or verifications, for nearly every theory-if we look for confirmations. Confirmations should count only if they are the result of risky predictions... A theory which is not refutable by any conceivable event is non-scientific. Irrefutability is not a virtue of a theory (as people often think) but a vice. Every genuine test of a theory is an attempt to falsify it, or refute it.
Karl Popper