There can be no ultimate statements science: there can be no statements in science which can not be tested, and therefore none which cannot in principle be refuted, by falsifying some of the conclusions which can be deduced from them.
Karl PopperWe do not know anything - this is the first. Therefore, we should be very modest - this is the second. Not to claim that we do know when we do not - this is the third. That's the kind of attitude I'd like to popularize. There is little hope for success.
Karl Popper