Call it nature or nurture, there are differences in how men and women approach professional conduct, and facing these issues head-on will make us all more equipped to succeed.

It's fantastic to be known as a company that responds quickly to users, shares great resources and friendly banter with them over Twitter, and forges relationships on Pinterest, Facebook, and every other social media site out there.

Most weeks, I work 100-plus hours on TheMuse.com. There are definitions of 'work-life balance' that would say I have none.

For almost the first year of The Muse's life, I would do 5 to 8 networking events a week. And I don't necessarily think that's the right path for everyone, but I realized that as an entrepreneur, one of my strengths was finding the right people who could help us. I didn't come into startups with any network.

If you're able to arrange a trial period with a new hire, do it. It will give both of you a chance to make sure the position is a good fit - and can help you avoid being in the awkward situation of wanting to fire someone three or four weeks in.

I've learned I'm rarely able to stay at home and not work. If I try to 'just sit on my couch for a little while,' I am going to grab my laptop and just knock out a few more emails, or start sketching up some product ideas for TheMuse.com. So when I want time off, I schedule dinners out, movie outings, and on occasion a flight lesson from Groupon.

What do I want to do with my life?