I think that one of the many advantages of death accruing over a long period of time is that you do have time to meet a lot of other people who are going through similar situations and one of the great delights of our life actually was sitting around in labs waiting for the results of tests and talking to other people who were waiting to find out whether their cancer numbers were going in the right direction or not.

Confidentiality is an ancient and well-warranted social value.

Manic-depression distorts moods and thoughts, incites dreadful behaviors, destroys the basis of rational thought, and too often erodes the desire and will to live. It is an illness that is biological in its origins, yet one that feels psychological in the experience of it, an illness that is unique in conferring advantage and pleasure, yet one that brings in its wake almost unendurable suffering and, not infrequently, suicide.

I think that for thousands of years people have made the observation that there are certain kinds of extreme depressive states that seem to be more likely to produce philosophers, people in the arts, unusually brilliant scientists.

There is a particular kind of pain, elation, loneliness, and terror involved in this kind of madness. When you're high it's tremendous. The ideas and feelings are fast and frequent like shooting stars....But, somewhere, this changes. The fast ideas are far too fast, and there are far too many; overwhelming confusion replaces clarity. Everything previously moving with the grain is now against-you are irritable, angry, frightened, uncontrollable....It will never end, for madness carves its own reality.

In depression, your capacity to feel just flattens and disappears and what you feel is pain and a kind of pain that you can't describe to anybody. So it's an isolating pain, a completely isolating pain.

There is an assumption, in attaching Puritan concepts such as 'successful' and 'unsuccessful' to the awful, final act of suicide, that those who 'fail' at killing themselves not only are weak, but incompetent, incapable even of getting their dying quite right.