Medicine really matured me as a person because, as a physician, you're obviously dealing with life and death issues, issues much more serious than what we're talking about in entertainment. You can't get more serious than life and death. And if you can handle that, you can handle anything.

There's really no substitute for working hard. I think that's my biggest talent. There are always people who are funnier and more talented than I am, but I don't take anything for granted and I commit myself 100% to each of my roles.

I'm very blessed that I have such a supportive wife who is secure with letting me embarrass myself.

It was my wife that insisted I do 'The Hangover.

It was such an amazing feeling to be on that movie set. And for the first scene I ever did in any movie, I improvised for about 10 minutes, and then there's applause by the crew, you know what I mean? I haven't had that before or since. It was just such an amazing moment.

You can have all the tools in the world but if you don't genuinely believe in yourself, it's useless.

I always just loved to laugh. I always just loved it as a kid.